drugset / Trial / NCT01449578

Dexpramipexole SAD/MAD Study

NCT01449578

Phase 1 Completed 63 enrolled Knopp Biosciences
RandomizedSingle-groupDouble-blindTreatment

Summary

This Phase 1 study will explore the safety, tolerability, and pharmacokinetics of single doses ranging from 300 to 600 mg and multiple daily doses ranging from 225 mg to 300 mg BID dexpramipexole in healthy volunteers.

Timeline

Start
2011-11
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexpramipexole Small molecule 225 mg Oral
Subject Dexpramipexole Small molecule 300 mg Oral
Subject Dexpramipexole Small molecule 600 mg Oral