drugset / Trial / NCT01457118

An Extension Study of NKTR-102 in Cancer Patients Previously Enrolled in NKTR-102 Studies

NCT01457118

Phase 2 Completed 27 enrolled Nektar Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

The study objective of this open label, multicenter study is to provide access to NKTR-102 treatment to subjects previously enrolled in a NKTR-102 study who are without signs of disease progression since receiving NKTR-102. In addition the study will evaluate the safety of continued exposure to NKTR-102, observe disease status and survival status in subjects receiving NKTR-102, and evaluate the efficacy of NKTR-102 in subjects with advanced or metastatic solid tumors.

Timeline

Start
2011-10
Primary completion
2017-08
Completion
2017-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Etirinotecan Pegol Other / unclassified 50 mg/m2 Intravenous
Subject Etirinotecan Pegol Other / unclassified 95 mg/m2 Intravenous
Subject Etirinotecan Pegol Other / unclassified 120 mg/m2 Intravenous
Subject Etirinotecan Pegol Other / unclassified 145 mg/m2 Intravenous

Indications