drugset / Trial / NCT01458015
Tapentadol Versus Oxycodone - a Mechanism-based Treatment Approach in Neuropathic Pain
RandomizedParallel-groupOpen-labelOther
Summary
The purpose of this study is to elucidate whether the additional mechanism of analgesia, i.e. reuptake inhibition of norepinephrine, of tapentadol leads to a change in different pain signs and symptoms in comparison to oxycodone.
Timeline
- Start
- 2011-10
- Primary completion
- 2013-11
- Completion
- 2013-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Oxycodone | Other / unclassified | 20 mg | — |
| Comparator | Oxycodone | Other / unclassified | 120 mg | — |
| Comparator | Tapentadol | Small molecule | 100 mg | — |
| Comparator | Tapentadol | Small molecule | 500 mg | — |