drugset / Trial / NCT01458015

Tapentadol Versus Oxycodone - a Mechanism-based Treatment Approach in Neuropathic Pain

NCT01458015

Phase 4 Terminated 3 enrolled University Hospital Schleswig-Holstein
RandomizedParallel-groupOpen-labelOther

Summary

The purpose of this study is to elucidate whether the additional mechanism of analgesia, i.e. reuptake inhibition of norepinephrine, of tapentadol leads to a change in different pain signs and symptoms in comparison to oxycodone.

Timeline

Start
2011-10
Primary completion
2013-11
Completion
2013-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Oxycodone Other / unclassified 20 mg
Comparator Oxycodone Other / unclassified 120 mg
Comparator Tapentadol Small molecule 100 mg
Comparator Tapentadol Small molecule 500 mg

Indications