drugset / Trial / NCT01461746

Efficacy Study of Chemotherapy Followed by Radiation Therapy to Treat Endometrial Cancer

NCT01461746 ↗

NaSingle-groupOpen-labelTreatment

Summary

Previous some studies suggested the addition of chemotherapy to radiation therapy after surgery may have survival benefit in patients with high risk endometrial cancer. In addition, docetaxel plus cisplatin regimen may have similar efficacy with paclitaxel plus carboplatin which is currently used in most cases. However, docetaxel plus cisplatin may cause less toxicity compared to paclitaxel plus carboplatin. Therefore, the investigators aimed to analyze the efficacy of docetaxel plus cisplatin regimen followed by radiation therapy after surgery in patients with high risk endometrial cancer.

Timeline

Start
2011-10
Primary completion
2017-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 60 mg/m2 —
Subject Docetaxel Small molecule 70 mg/m2 —

Indications