Effects of Azithromycin on Airway Oxidative Stress Markers in Patients With Bronchiectasis

Summary

The mechanism by which macrolide antibiotics have immune modifying effects independent from its antibacterial activity has not been well established. In the present work, the investigators will analyze the effect of long-term treatment with azithromycin (250 mg three times per week during three months) on airway oxidative stress markers in exhaled breath condensate of adult patients with stable non-CF bronchiectasis.

Timeline

Start

2006-10

Primary completion

2007-04

Completion

2007-09

Drugs

Indications