drugset / Trial / NCT01464125
Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults
Phase 2
Unknown
43 enrolled
Jomaa Pharma GmbH
Mahidol University · collabThammasat University · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The aim of this study is to evaluate the role of azithromycin as a possible combination partner for fosmidomycin to protect it from its susceptibility to recrudescent infections when used as monotherapy for acute Plasmodium falciparum malaria while retaining its excellent safety profile.
Timeline
- Start
- 2008-11
- Primary completion
- 2009-10
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Azithromycin | Small molecule | 750 mg | — |
| Subject | Fosmidomycin | Small molecule | 1800 mg | — |