drugset / Trial / NCT01464138
Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children
Phase 2
Completed
52 enrolled
Jomaa Pharma GmbH
Fundacio Clinic Barcelona · collabHospital Clinic of Barcelona · collab
NaSingle-groupOpen-labelTreatment
Summary
This is an open label uncontrolled study to determine the efficacy of fosmidomycin and clindamycin when co-administered orally over three days in the treatment of acute uncomplicated Plasmodium falciparum malaria in children. The primary study endpoints will be the cure rate on Day 28 (PCR corrected). The secondary endpoints will be the cure rate on Day 7 and the parasite and fever clearance times.
Timeline
- Start
- 2010-09
- Primary completion
- 2011-09
- Completion
- 2011-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clindamycin | Unknown | 10 mg/kg | Oral |
| Subject | Fosmidomycin | Small molecule | 30 mg/kg | Oral |