drugset / Trial / NCT01468532

Docetaxel, Prednisone, and Pasireotide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

NCT01468532

NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the side effects and best dose of pasireotide and to see how well it works when given together with docetaxel and prednisone in treating patients with metastatic hormone-resistant prostate cancer. Drugs used in chemotherapy, such as docetaxel and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Pasireotide may inhibit the secretion of hormones. Giving pasireotide together with docetaxel and prednisone may kill more tumor cells.

Timeline

Start
2011-10
Primary completion
2017-07-20
Completion
2017-07-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Pasireotide Other / unclassified 40 mg Intramuscular
Background Docetaxel Small molecule 75 mg/m2 Intravenous
Background Prednisone Other / unclassified 5 mg Oral