drugset / Trial / NCT01469598

Study of Docetaxel and Gemcitabine in Metastatic Esophageal Squamous Cell Cancer

NCT01469598 ↗

Phase 2 Completed 24 enrolled Samsung Medical Center
NaSingle-groupOpen-labelTreatment

Summary

Gemcitabine is a novel analog of the nucleoside deoxycytidine that acts via inhibition of DNA synthesis.Docetaxel is a semisynthetic taxane and promotes microtubule assembly and inhibits microtubule depolymerization. In this study, patients received gemcitabine 900 mg/m2 on days 1 and 8 plus docetaxel 100 mg/m2 on day 8 with G-CSF support every 3 week.

Timeline

Start
2011-08
Primary completion
2014-02
Completion
2015-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 35 mg/m2 Intravenous
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous