drugset / Trial / NCT01469910
Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of Simotinib Hydrochloride in Healthy Subjects
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the safety and pharmacokinetics of single ascending doses of Simotinib Hydrochloride in healthy subjects.
Timeline
- Start
- 2011-09
- Primary completion
- 2012-06
- Completion
- 2012-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Simotinib | Small molecule | 25 mg | — |
| Subject | Simotinib | Small molecule | 50 mg | — |
| Subject | Simotinib | Small molecule | 100 mg | — |
| Subject | Simotinib | Small molecule | 150 mg | — |
| Subject | Simotinib | Small molecule | 225 mg | — |
| Subject | Simotinib | Small molecule | 300 mg | — |
| Subject | Simotinib | Small molecule | 400 mg | — |
| Subject | Simotinib | Small molecule | 500 mg | — |
| Subject | Simotinib | Small molecule | 600 mg | — |
| Subject | Simotinib | Small molecule | 750 mg | — |
Indications
No indication recorded.