drugset / Trial / NCT01471288
Effect of Carum Carvi on Thyroid Hormones and TSH Level
Phase 1/2
Unknown
40 enrolled
Mashhad University of Medical Sciences
Pharmaceutical Research Center · collab
RandomizedParallel-groupQuadruple-blindBasic science
Summary
Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.
Timeline
- Start
- 2011-05
- Primary completion
- 2011-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | CARAWAY | Traditional medicine (herbal / TCM) | 40 mg/kg | — |