drugset / Trial / NCT01472380
A Drug-Drug Interaction Study Between Fenofibric Acid and Efavirenz
Non-randomizedSingle-groupOpen-labelBasic science
Summary
Efavirenz is predominantly metabolized by cytochrome P450 (CYP) 2B6. Fenofibric Acid is an inhibitor of CYP2B6. This study will evaluate the effect of multiple doses of fenofibric acid at steady-state on the pharmacokinetics of single-dose efavirenz in healthy adult subjects.
Timeline
- Start
- 2011-11
- Primary completion
- 2011-12
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Efavirenz | Other / unclassified | 600 mg | Oral |
| Comparator | fenofibric acid | Small molecule | 105 mg | Oral |
Indications
No indication recorded.