drugset
drugset / Trial / NCT01473173

Safety, Tolerability, PK, PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects

NCT01473173 ↗

Phase 1 Completed 59 enrolled HK inno.N Corporation
RandomizedParallel-groupDouble-blindBasic science

Summary

The objectives of this study are: * To evaluate the safety and tolerability of single and multiple oral doses of CJ-12420 in healthy male subjects. * To evaluate the single- and multiple-dose PK of orally administered CJ-12420 in healthy male subjects. * To evaluate the single- and multiple-dose PD of orally administered CJ-12420 in healthy male subjects. * To compare the multiple-dose pharmacodynamics (PD) of orally administered CJ-12420 and esomeprazole in healthy male subjects.

Timeline

Start
2011-11
Primary completion
2012-08
Completion
2012-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Esomeprazole Small molecule 40 mg Oral
Subject Tegoprazan Other / unclassified 50 mg Oral
Subject Tegoprazan Other / unclassified 100 mg Oral
Subject Tegoprazan Other / unclassified 200 mg Oral
Subject Tegoprazan Other / unclassified 400 mg Oral

Indications

No indication recorded.