drugset / Trial / NCT01479920
A Positron Emission Topographic (PET) Study on Depression Patient With Electroacupuncture
Completed
36 enrolled
The University of Hong Kong
Kowloon Hospital, Hong Kong · collabQueen Mary Hospital, Hong Kong · collabSouthern Medical University, China · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
This is a randomized, assessor-blind, placebo controlled study in major depressive disorder (MDD) patients. Subjects receiving antidepressant drug (FLX) would be assigned to receive either 18 sham / active DCEAS for in 6 weeks. Changes in the severity of depressive symptoms over time are measured using depression rating scales. Brain glucose metabolic levels are measured using PET at baseline and endpoint. The most intriguing and expected result might be that acupuncture treated-patients may display comparable or even better outcomes and the clinical improvements by acupuncture are correlated with the restoration of the activities in the related brain regions.
Timeline
- Start
- 2012-06
- Primary completion
- 2015-05
- Completion
- 2015-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluoxetine | Small molecule | 10 mg | Oral |
| Comparator | Fluoxetine | Small molecule | 30 mg | Oral |