drugset / Trial / NCT01490255

Pharmacodynamic Effects of Ranolazine Versus Amlodipine on Platelet Reactivity

NCT01490255

Phase 4 Unknown 100 enrolled University of Roma La Sapienza
RandomizedCrossoverSingle-blindDiagnostic

Summary

No previous study has assessed the potential of ranolazine to interfere with levels of platelet reactivity in patients with coronary artery disease who are treated with dual antiplatelet therapy. Aim of this study is to compare the pharmacodynamic effects of maintenance doses of ranolazine versus amlodipine on platelet reactivity in patients with coronary artery disease who are treated with dual antiplatelet therapy.

Timeline

Start
2012-01
Primary completion
2014-06
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amlodipine Other / unclassified 10 mg Other
Comparator Ranolazine Small molecule 750 mg Other