drugset / Trial / NCT01490294
Myocardial Perfusion MRI
RandomizedParallel-groupTriple-blindDiagnostic
Summary
The object of this study is to compare four different dosages of Gadavist 1.0 in cardiac Magnetic Resonance Tomography (MRT) imaging with the imaging results of a cardiac SPECT examination in terms of diagnostic quality. For this purpose Gadavist dosages of 0.01 mmol/kg, 0.025 mmol/kg, 0.05 mmol/kg or 0.1mmol/kg body weight are administered. A study participant receives the respective dose twice i.e. at rest and at stress using Adenosine (which puts circulation into a state of stress similar to that of physical exercise). The time between both injections is 10-15 min. The total imaging time is about 45 min.
Timeline
- Start
- 2004-03
- Primary completion
- 2006-05
- Completion
- 2006-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gadobutrol | Diagnostic / imaging agent | 0.01 mmol | Intravenous |
| Subject | Gadobutrol | Diagnostic / imaging agent | 0.025 mmol | Intravenous |
| Subject | Gadobutrol | Diagnostic / imaging agent | 0.05 mmol | Intravenous |
| Subject | Gadobutrol | Diagnostic / imaging agent | 0.1 mmol | Intravenous |
Indications
No indication recorded.