Ranolazine Loading to Prevent PCI-induced Myocardial Injury

Summary

It has previously been shown that pretreatment with ranolazine 1,000 mg twice daily for 7 days can significantly reduce procedural myocardial injury in elective percutaneous coronary intervention (PCI). The investigators tested the hypothesis that twice overnight high-dose ranolazine loading before PCI can reduce the peri-procedural myocardial ischemic damage similarly to long-term pre-treatment with standard doses.

Timeline

Start

2014-01

Primary completion

2015-12

Completion

2017-12

Drugs

Indications