Effect of Antidepressants on White Matter Structure

Summary

Subjects with major depression will be evaluated and intensively characterized through questionnaires, computerized cognitive evaluation and laboratory investigations. Magnetic resonance imaging will be used to document baseline white matter structure. subjects will then receive desvenlafaxine which will be adjusted as clinically indicated. After 16 weeks the evaluations will be repeated.

Timeline

Start

2011-11

Primary completion

2013-09

Completion

2013-11

Drugs

Indications