drugset / Trial / NCT01493869

Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects

NCT01493869

Phase 1 Completed 26 enrolled Exelixis
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The main objective of this study is to compare the pharmacokinetics (PK) of a single oral 75 mg dose of cabozantinib in hepatic impaired adult subjects to healthy adult subjects. Another objective is to assess the safety and tolerability of cabozantinib in these adult subjects.

Timeline

Start
2011-09
Primary completion
2014-05
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 75 mg Oral

Indications

No indication recorded.