drugset / Trial / NCT01495520

Ranolazine for Improving Symptoms of Palpitations

NCT01495520

Phase 4 Unknown 100 enrolled University of Roma La Sapienza
RandomizedCrossoverTriple-blindTreatment

Summary

Patients with ischemic heart disease often report multiple symptoms, including angina and palpitations. Ranolazine has antiarrhythmic effects which are largely a result of the drug's effect on multiple ion channels. It remains unknown, however, whether the favorable effects of ranolazine on symptoms and arrhythmias are maintained over time. Aim of this study is to test the hypothesis that chronic treatment with ranolazine can improve the symptomatic status of patients with ischemic heart disease by reducing the occurrence of palpitations.

Timeline

Start
2014-01
Primary completion
2014-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ranolazine Small molecule 750 mg Oral

Indications