drugset / Trial / NCT01497327
Open-Label Hepatic Impairment Study
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will be conducted in Hepatitis C positive patients to determine whether the pharmacodynamic effects of PSI-7977 or PSI-352938 are similar to HCV-infected patients with normal hepatic function, which may allow inclusion of patients with cirrhosis and varying degrees of hepatic dysfunction in future clinical studies.
Timeline
- Start
- 2011-07
- Primary completion
- 2012-01
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PSI-352938 | Small molecule | 300 mg | Oral |
| Subject | Sofosbuvir | Small molecule | 400 mg | Oral |