Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas

Summary

The purpose of this study is to investigate whether weekly Vinorelbine treatment can shrink or slow the growth of pediatric low-grade gliomas that have either returned or are continuing to grow. Vinorelbine is a semi-synthetic vinca alkaloid that has recently generated interest in patients with pediatric low-grade glioma. It has been specifically synthesized to broaden its therapeutic spectrum and decrease the neurotoxicity associated with related agents.

Timeline

Start

2011-07

Primary completion

2017-01

Completion

2017-07

Drugs

Indications