Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma

Summary

This is a phase I study to investigate the safety and pharmacokinetics of weekly 5-fluorouracil (5-FU) administered as a bolus dose in children and young adults with recurrent or refractory ependymoma. The results from this study will inform a subsequent phase II St. Jude investigator-initiated trial.

Timeline

Start

2011-12

Primary completion

2014-05

Completion

2014-05

Drugs

Indications