drugset / Trial / NCT01500096
American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial
Phase 2
Completed
96 enrolled
Johns Hopkins University
National Center for Complementary and Integrative Health (NCCIH) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether American ginseng is effective in the treatment of HIV-associated fatigue.
Timeline
- Start
- 2013-02
- Primary completion
- 2016-09
- Completion
- 2016-09
Publications
- Background Andrade AS, Hendrix C, Parsons TL, Caballero B, Yuan CS, Flexner CW, Dobs AS, Brown TT. Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir. BMC Complement Altern Med. 2008 Aug 19;8:50. doi: 10.1186/1472-6882-8-50.
- Background Barton DL, Soori GS, Bauer BA, Sloan JA, Johnson PA, Figueras C, Duane S, Mattar B, Liu H, Atherton PJ, Christensen B, Loprinzi CL. Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA. Support Care Cancer. 2010 Feb;18(2):179-87. doi: 10.1007/s00520-009-0642-2. Epub 2009 May 6.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | American ginseng | Unknown | 1000 mg | Oral |
| Comparator | American ginseng | Unknown | 3000 mg | Oral |