Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

Summary

This phase I clinical trial investigates the side effects and the best dose of local (intrapleural measles virus therapy in treating patients with malignant pleural mesothelioma (MPM). The investigators anticipate that the intrapleural of the vaccine strain measles virus will enable the virus to specifically infect and kill cancer cells and spare, without damaging normal cells. Furthermore, the investigators expect the measles virus to trigger an anti-tumor immune response which will result in additional destruction of the tumor by immune cells

Timeline

Start

2011-11

Primary completion

2019-04-11

Completion

2019-04-11

Drugs

Indications