drugset / Trial / NCT01504126
Propranolol Hydrochloride and Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Phase 0
Completed
32 enrolled
M.D. Anderson Cancer Center
National Cancer Institute (NCI) · collabSprint for Life · collab
NaSingle-groupOpen-labelTreatment
Summary
This early phase I trial studies giving propranolol hydrochloride with standard chemotherapy in treating patients with ovarian, primary peritoneal, or fallopian tube cancer. Biological therapies, such as propranolol hydrochloride, blocks certain chemicals that affect the heart and this may stimulate the immune system and allow the chemotherapy to kill more tumor cells.
Timeline
- Start
- 2012-03-09
- Primary completion
- 2019-08-15
- Completion
- 2019-08-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propranolol | Small molecule | — | Oral |
Indications
fallopian tube clear cell adenocarcinoma
fallopian tube endometrioid adenocarcinoma
fallopian tube mucinous adenocarcinoma
fallopian tube serous adenocarcinoma
ovarian clear cell adenocarcinoma
ovarian endometrioid adenocarcinoma
ovarian mucinous adenocarcinoma
ovarian seromucinous carcinoma
ovarian serous adenocarcinoma
primary peritoneal serous adenocarcinoma
undifferentiated ovarian carcinoma