Efficacy and Safety Study of TRK-820 to Treat Conventional-treatment-resistant Pruritus in Patients Receiving Hemodialysis

Phase 3 Completed 104 enrolled SK Chemicals Co., Ltd. Toray Industries, Inc · collab

RandomizedFactorialDouble-blindTreatment

Summary

The purpose of this study is to determine whether nalfurafine hydrochloride is effective and safe in the treatment for conventional-treatment-resistant pruritus in patients receiving hemodialysis.

Timeline

Start: 2008-04
Primary completion: 2009-10
Completion: 2009-10

Publications

Hercz D, Jiang SH, Webster AC. Interventions for itch in people with advanced chronic kidney disease. Cochrane Database Syst Rev. 2020 Dec 7;12(12):CD011393. doi: 10.1002/14651858.CD011393.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Nalfurafine	Small molecule	2.5 ug	Oral
Comparator	Nalfurafine	Small molecule	5 ug	Oral

Indications

No indication recorded.