drugset / Trial / NCT01518621

Whole Brain Radiation With or Without Erlotinib for Brain Metastases From Non-Small Cell Lung Cancer

NCT01518621 ↗

Phase 2 Terminated 25 enrolled Oslo University Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

To determine if erlotinib given orally along with concurrent whole brain irradiation in lung cancer patients with brain metastases improves median overall survival and enhances local control compared to those treated with WBRT alone, without significantly increasing the risk of side effects or lowering quality of life.

Timeline

Start
2012-05
Primary completion
2017-12-10
Completion
2018-12-10

Outcome

Outcome not reported

Stopped (Enrollment): “Slow accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Erlotinib Small molecule 150 mg Oral

Indications