Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects

NCT01520012 ↗

Phase 1 Completed 44 enrolled Yuhan Corporation

RandomizedCrossoverOpen-labelTreatment

Summary

The main objective is to evaluate the food effect on the pharmacokinetic profile of YH4808 100 mg b.i.d and YH4808 300 mg after oral administration in healthy male subjects.

Timeline

Start: 2012-02
Primary completion: 2012-05
Completion: 2012-06

Publications

Kim E, Kim A, Yi S, Kim YK, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS, Lee S. Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects. Eur J Clin Pharmacol. 2018 Oct;74(10):1261-1272. doi: 10.1007/s00228-018-2502-9. Epub 2018 Jun 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	YH4808	Other / unclassified	100 mg	Oral
Subject	YH4808	Other / unclassified	300 mg	Oral

Indications

No indication recorded.