drugset / Trial / NCT01520389

Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment

NCT01520389

Phase 1 Completed 112 enrolled Merrimack Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study is a Phase 1 and pharmacologic open-labeled dose-escalation trial using a "3+3" design, evaluating MM-151 at varying dose levels and frequencies, and subsequently in combination with irinotecan.

Timeline

Start
2012-01
Primary completion
2015-12
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Subject MM-151 Unknown
Background Irinotecan Small molecule 180 mg/m2