Early Immune Responses to Inactivated Influenza Vaccine: a Pilot Study

Completed 20 enrolled Johns Hopkins Bloomberg School of Public Health

RandomizedSingle-groupOpen-labelBasic science

Summary

Some people experience symptoms just after receiving the seasonal inactivated influenza vaccine. The cause of some of these symptoms is likely to be an immune response to the vaccine. The investigators would like to look at the earliest immune responses to the inactivated influenza vaccine. This pilot study will help us to determine at what time points we should look.

Timeline

Start: 2012-01
Primary completion: 2012-02
Completion: 2012-02

Publications

Results Talaat KR, Halsey NA, Cox AB, Coles CL, Durbin AP, Ramakrishnan A, Bream JH. Rapid changes in serum cytokines and chemokines in response to inactivated influenza vaccination. Influenza Other Respir Viruses. 2018 Mar;12(2):202-210. doi: 10.1111/irv.12509. Epub 2018 Jan 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Influenza Virus Vaccine	Vaccine	0.5 ml	Intramuscular

Indications

No indication recorded.