drugset / Trial / NCT01522417

Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention

NCT01522417

Phase 2 Completed 535 enrolled Medicure SCRI Development Innovations, LLC · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose this study is to assess whether a tirofiban regimen of a high-dose bolus plus a shortened infusion duration compared to label-dosing eptifibatide in patients undergoing percutaneous coronary intervention (PCI) is associated with a non-inferior composite rate of death, PCI-related myocardial infarction, urgent target vessel revascularization or in-hospital major bleeding within 48 hours following PCI or hospital discharge, whichever comes first.

Timeline

Start
2012-04
Primary completion
2018-12
Completion
2019-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Eptifibatide Other / unclassified 2 ug/kg
Subject Tirofiban Other / unclassified 0.15 ug/kg Intravenous