drugset / Trial / NCT01522417
Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose this study is to assess whether a tirofiban regimen of a high-dose bolus plus a shortened infusion duration compared to label-dosing eptifibatide in patients undergoing percutaneous coronary intervention (PCI) is associated with a non-inferior composite rate of death, PCI-related myocardial infarction, urgent target vessel revascularization or in-hospital major bleeding within 48 hours following PCI or hospital discharge, whichever comes first.
Timeline
- Start
- 2012-04
- Primary completion
- 2018-12
- Completion
- 2019-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Eptifibatide | Other / unclassified | 2 ug/kg | — |
| Subject | Tirofiban | Other / unclassified | 0.15 ug/kg | Intravenous |