drugset / Trial / NCT01523496
Vitamin D Supplementation in HIV Youth
Phase 2/3
Completed
190 enrolled
University Hospitals Cleveland Medical Center
Emory University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine the correct dose of Vitamin D to give to prevent HIV related complications.
Timeline
- Start
- 2011-12
- Primary completion
- 2016-08
- Completion
- 2016-08
Publications
- Eckard AR, O'Riordan MA, Rosebush JC, Lee ST, Habib JG, Ruff JH, Labbato D, Daniels JE, Uribe-Leitz M, Tangpricha V, Chahroudi A, McComsey GA. Vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youth. Antivir Ther. 2018;23(4):315-324. doi: 10.3851/IMP3199.
- Eckard AR, Rosebush JC, O'Riordan MA, Graves CC, Alexander A, Grover AK, Lee ST, Habib JG, Ruff JH, Chahroudi A, McComsey GA. Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activation. Antivir Ther. 2017;22(8):669-680. doi: 10.3851/IMP3157.
- Hileman CO, Overton ET, McComsey GA. Vitamin D and bone loss in HIV. Curr Opin HIV AIDS. 2016 May;11(3):277-84. doi: 10.1097/COH.0000000000000272.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Vitamin D | Other / unclassified | 18000 iu | — |
| Comparator | Vitamin D | Other / unclassified | 60000 iu | — |
| Comparator | Vitamin D | Other / unclassified | 120000 iu | — |