Improving Learning-based Treatment of Cocaine Dependence With Medication

Phase 2 Completed 52 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will test the efficacy of d-cycloserine in enhancing response to learning-based treatment for cocaine dependence, specifically contingency management.

Timeline

Start: 2011-09
Primary completion: 2013-03
Completion: 2013-03

Publications

Johnson MW, Bruner NR, Johnson PS, Silverman K, Berry MS. Randomized controlled trial of d-cycloserine in cocaine dependence: Effects on contingency management and cue-induced cocaine craving in a naturalistic setting. Exp Clin Psychopharmacol. 2020 Apr;28(2):157-168. doi: 10.1037/pha0000306. Epub 2019 Aug 1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cycloserine	Small molecule	50 mg	—

Improving Learning-based Treatment of Cocaine Dependence With Medication

Summary

Timeline

Publications

Drugs

Indications