Deacylated Ghrelin and Beta Cell Function

Unknown 30 enrolled David Dalessio National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab

RandomizedCrossoverSingle-blind

Summary

Use of human unacylated ghrelin (UAG, also called des-octanoyl ghrelin) to study physiology in healthy subjects. The proposed research is an investigator-initiated study funded by the National Institutes of Health designed to examine the effect of physiologic levels of UAG on the regulation of glucose homeostasis as well as beta cell function.

Timeline

Start: 2011-02
Primary completion: 2013-04
Completion: —

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ghrelin	Peptide	1 ug/kg	Intravenous
Subject	Ghrelin	Peptide	4 ug/kg	Intravenous
Subject	combined acyl and desacyl ghrelin	Unknown	4 ug/kg	Intravenous

Indications

No indication recorded.