drugset / Trial / NCT01531439

Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery

NCT01531439

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose. The trial is designed to determine if a higher dose of naloxone infusion will reduce side effects from opioid therapy in patients who have undergone spine fusion for scoliosis.

Timeline

Start
2011-11
Primary completion
2015-05-01
Completion
2016-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Naloxone Small molecule 0.5 ug/kg
Subject Naloxone Small molecule 2.5 ug/kg

Indications