drugset / Trial / NCT01531439
Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose. The trial is designed to determine if a higher dose of naloxone infusion will reduce side effects from opioid therapy in patients who have undergone spine fusion for scoliosis.
Timeline
- Start
- 2011-11
- Primary completion
- 2015-05-01
- Completion
- 2016-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naloxone | Small molecule | 0.5 ug/kg | — |
| Subject | Naloxone | Small molecule | 2.5 ug/kg | — |