drugset / Trial / NCT01533220

Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal

NCT01533220

Phase 3 Completed 132 enrolled EMS
RandomizedParallel-groupTriple-blindTreatment

Summary

The common cold is a major cause of nasal obstruction and reaches children and adults two or more times a year. At the moment, there is no cure for the common cold, and therefore the reduction of symptoms is the focus of the treatment. The study has parallel distribution design, with two equal groups, in which one group will be treated by a combination of naphazoline hydrocloride + pheniramine maleate + panthenol and the other will receive treatment with naphazoline hydrocloride.

Timeline

Start
2013-01-01
Primary completion
2013-08-31
Completion
2014-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Panthenol Unknown 5 mg Intranasal
Comparator naphazoline hydrocloride Unknown 0.5 mg Intranasal
Comparator naphazoline hydrocloride Unknown 1 mg Intranasal
Subject pheniramine Small molecule 0.2 mg Intranasal