drugset / Trial / NCT01536951

A Study of LY3009104 in Healthy Participants

NCT01536951

Phase 1 Completed 62 enrolled Eli Lilly and Company Incyte Corporation · collab
RandomizedCrossoverDouble-blindBasic science

Summary

This will be a 2-part, randomized, participant- and investigator-blind study in healthy males and females. Part A of this study is to determine a safe and tolerable single oral dose of LY3009104 that yields drug exposures slightly exceeding typical exposures anticipated from repeated administration of an efficacious dose to participants. The concentration of the drug in the blood stream will be measured and information about any side effects that may occur will also be collected. Part B of this study is to evaluate the effect of LY3009104 on the electrical activity of the heart as measured by electrocardiogram (ECG) in relation to placebo following a single oral dose.

Timeline

Start
2012-02
Primary completion
2013-05
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Baricitinib Small molecule 40 mg Oral
Comparator Moxifloxacin Small molecule 400 mg Oral

Indications

No indication recorded.