drugset / Trial / NCT01537575

Intravenous Immunoglobulins for Post-Polio Syndrome

NCT01537575

RandomizedParallel-groupDouble-blindTreatment

Summary

Postpolio syndrome is a condition that affects many polio survivors years after the acute infection and causes symptoms to increase or new symptoms to develop. Proinflammatory cytokine production within the central nervous system (CNS) indicates an underlying inflammatory process, amenable to immunomodulatory therapy. In this study the investigators sought to confirm that antiinflammatory treatment with intravenous immunoglobulin improves the disease.

Timeline

Start
2008-01
Primary completion
2009-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Immune Globulin Intravenous (Human) Protein / enzyme biologic 0.4 g/kg Intravenous