Clinical Trial to Evaluate the Efficacy of Smoking Cessation

Summary

The purpose of this study is to assess the efficacy of smoking cessation by using varenicline as monotherapy (VRN + placebo patches) or combined therapy (VRN + nicotine patches).

Timeline

Start

2012-01

Primary completion

2013-06

Completion

2013-06

Outcome

Missed primary endpoint

paper The combination of the nicotine patch with varenicline was not associated with higher rates of continuous abstinence at 12 weeks PMID 25296623 ↗

Publications

• Livingstone-Banks J, Fanshawe TR, Thomas KH, Theodoulou A, Hajizadeh A, Hartman L, Lindson N. Nicotine receptor partial agonists for smoking cessation. Cochrane Database Syst Rev. 2023 May 5;5(5):CD006103. doi: 10.1002/14651858.CD006103.pub8.
• Ramon JM, Morchon S, Baena A, Masuet-Aumatell C. Combining varenicline and nicotine patches: a randomized controlled trial study in smoking cessation. BMC Med. 2014 Oct 8;12:172. doi: 10.1186/s12916-014-0172-8.

Drugs

Indications

No indication recorded.