drugset / Trial / NCT01538563

Safety of 24-Hour Infusion of ON 01910.Na in Patients With Advanced Cancer

NCT01538563

Phase 1 Completed 42 enrolled Traws Pharma, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The primary purpose of this study is to determine the highest dose of ON 01910.Na that can be safely given as an intravenous infusion over 24 hours once a week in a 3-week cycle to patients with advanced solid tumors.

Timeline

Start
2006-06
Primary completion
2010-07
Completion
2011-11

Publications

  • Results Garcia-Manero G, Fenaux P. Comprehensive Analysis of Safety: Rigosertib in 557 Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML). Blood Dec 2016, 128 (22) 2011; ASH 2016.

Drugs

EvaluationDrugModalityDoseRoute
Subject rigosertib Small molecule 2400 mg/m2 Intravenous

Indications