drugset / Trial / NCT01542047

A Combination of Pazopanib and Carboplatin in Advanced Solid Malignancies

NCT01542047

NaSingle-groupOpen-labelTreatment

Summary

This study is designed to investigate the possibility that use of two similar but distinct drugs used together in treatment of advanced cancer might prove less toxic than either agent used alone, because dosages can be reduced for each agent. This is a phase I study that is designed to measure the frequency and levels of specific side effects when Carboplatin and Pazopanib are used in combination in advanced cancer patients. The possibility that anti-tumor activity will occur is also going to be investigated.

Timeline

Start
2012-08
Primary completion
2013-02
Completion
2013-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Pazopanib Small molecule 200 unknown Oral
Subject Pazopanib Small molecule 800 unknown Oral