drugset / Trial / NCT01543529

A Pharmacodynamic and Pharmacokinetic Study of RO4917838 in Healthy Volunteers

NCT01543529

Phase 1 Completed 25 enrolled Hoffmann-La Roche
RandomizedCrossoverDouble-blindOther

Summary

This single-center, randomized, double-blind, four-period crossover study will investigate the effect of alcohol on the pharmacodynamics and pharmacokinetics of RO4917838 in healthy volunteers. Healthy volunteers will receive 4 treatments in a randomized order: single dose of RO4917838 and alcohol, RO4917838 and non-alcoholic drink, placebo to RO4917838 and alcohol, and placebo to RO4917838 and non-alcoholic drink.

Timeline

Start
2012-02-28
Primary completion
2012-06-04
Completion
2012-06-04

Drugs

EvaluationDrugModalityDoseRoute
Subject bitopertin Small molecule

Indications

No indication recorded.