Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Summary

This protocol is a phase I/II, study of ascorbic acid (AA) infusions combined with treatment with irinotecan versus treatment with irinotecan alone in patients with recurrent or advanced colorectal cancer who have failed at least one treatment regimen with a 5-FU based therapy. This study will be conducted as an amendment to Investigational New Drug # 77486.

Timeline

Start

2011-12

Primary completion

2015-02

Completion

2015-02

Outcome

Outcome not reported

Stopped (Enrollment): “Closed: low enrollment, many treatment options available for Colorectal Cancer”

Drugs

Indications