drugset / Trial / NCT01551459

A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma

NCT01551459

RandomizedCrossoverOpen-labelTreatment

Summary

Doctors usually treat uveal melanoma with radiotherapy or surgery. But if this cancer spreads, it is more difficult to treat. Doctors usually treat uveal melanoma that has spread with a chemotherapy called dacarbazine, but they are always looking to find new ways to treat uveal melanoma. This study aims to find out how well Sunitinib works to treat uveal melanoma and to see how long Sunitinib and Dacarbazine can help to prevent the cancer from getting worse.

Timeline

Start
2010-10
Primary completion
2017-09
Completion
2017-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dacarbazine Small molecule 1000 mg/m2 Intravenous
Subject Sunitinib Small molecule 50 mg Oral

Indications