Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Phase 4 Completed 464 enrolled Shire

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine effectiveness of Vyvanse compared to Concerta in adolescents with Attention-deficit/Hyperactivity Disorder (ADHD).

Timeline

Start: 2012-04-17
Primary completion: 2014-01-22
Completion: 2014-01-22

Publications

Newcorn JH, Nagy P, Childress AC, Frick G, Yan B, Pliszka S. Randomized, Double-Blind, Placebo-Controlled Acute Comparator Trials of Lisdexamfetamine and Extended-Release Methylphenidate in Adolescents With Attention-Deficit/Hyperactivity Disorder. CNS Drugs. 2017 Nov;31(11):999-1014. doi: 10.1007/s40263-017-0468-2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lisdexamfetamine Dimesylate	Small molecule	30 mg	Oral
Subject	Lisdexamfetamine Dimesylate	Small molecule	70 mg	Oral
Comparator	Methylphenidate	Small molecule	18 mg	Oral
Comparator	Methylphenidate	Small molecule	72 mg	Oral

Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Summary

Timeline

Publications

Drugs

Indications