drugset / Trial / NCT01554189
A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-8325 in Hepatitis C-Infected Males (MK-8325-002)
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is being done to assess the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of MK-8325 in male hepatitis C virus (HCV)-infected participants. There will be 3 parts to this study. Part I will enroll only genotype 1 (GT1) HCV patients, Part II will enroll only genotype 3 (GT3) HCV-infected participants, and Part III will enroll only GT1a HCV-infected participants. All parts may run concurrently, or may be staggered as needed by the clinical sites.
Timeline
- Start
- 2012-04
- Primary completion
- 2013-04
- Completion
- 2013-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MK-8325 | Unknown | 10 mg | Oral |
| Subject | MK-8325 | Unknown | 50 mg | Oral |
| Subject | MK-8325 | Unknown | 100 mg | Oral |
| Subject | MK-8325 | Unknown | 200 mg | Oral |