drugset / Trial / NCT01554293

Study Of Single Ascending Doses Of PBL 1427 In Healthy Volunteers

NCT01554293 ↗

Phase 1 Unknown 48 enrolled Panacea Biotec Ltd
RandomizedParallel-groupQuadruple-blindTreatment

Summary

PBL 1427 is a Dipeptidyl peptidase (DPP)-IV inhibitor being developed for treatment of type 2 diabetes. Although a number of DPP-IV inhibitors have been described, there still exists a need for new DPP-IV inhibitors that have better half-life, advantageous potency, stability and selectivity, less toxicity and/or better pharmacodynamic properties.

Timeline

Start
2012-07
Primary completion
2013-07
Completion
2013-09

Drugs

EvaluationDrugModalityDoseRoute
Subject PBL 1427 Unknown 20 mg Oral
Subject PBL 1427 Unknown 40 mg Oral
Subject PBL 1427 Unknown 80 mg Oral
Subject PBL 1427 Unknown 150 mg Oral
Subject PBL 1427 Unknown 300 mg Oral
Subject PBL 1427 Unknown 600 mg Oral

Indications