Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia

Summary

Cognitive training is moderately effective at reducing symptoms and improving life function in schizophrenia patients. The present application develops a strategy for increasing the effectiveness of cognitive training through the use of pro-cognitive medications. Specific biomarkers will be studied that identify patients most sensitive to these pro-cognitive medications, to test the feasibility of using these biomarkers in a large clinical trial of medication-enhanced cognitive training in schizophrenia.

Timeline

Start

2014-07

Primary completion

2019-06-01

Completion

2019-06-01

Drugs

Indications