drugset / Trial / NCT01557712

Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks

NCT01557712

Phase 3 Completed 25 enrolled University Hospital, Grenoble
RandomizedSingle-groupTriple-blindTreatment

Summary

The objective of this study is to evaluate the effectiveness of ketamine (infusion of 0.5mg/kg) and venlafaxine compared to the use of venlafaxine alone in the treatment of major depression (MADRS score ≥ 20 ) to six weeks of treatment.

Timeline

Start
2012-03
Primary completion
2017-01
Completion
2017-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.5 mg/kg Intravenous
Background Venlafaxine Small molecule 150 mg
Background Venlafaxine Small molecule 375 mg